< Back Alogliptin and metformin Common Brand Names: Kazano Drug Class Antidiabetic combinations Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Type 2 diabetes mellitus Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Sevoflurane Common Brand Names: Sojourn, Ultane Drug Class General anesthetics Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Cause sleep during a procedure Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

What is alpha-gal syndrome? Alpha-gal syndrome (AGS), or mammalian meat allergy, is a serious allergic reaction to galactose-α-1,3-galactose—a sugar molecule called alpha-gal—found in most non-primate mammals (e.g., cow, pig, sheep, venison, rabbit). Most people develop AGS after a tick bite, which triggers the immune system to produce IgE antibodies against alpha-gal. Reactions can be immediate (e.g., from medications with mammalian ingredients) or delayed—often 2 to 10+ hours after eating red meat or other mammalian products. Pill Clarity helps both patients with AGS and healthcare professionals caring for them every day, providing guidance on alpha-gal friendly health products. Key Statistics: 450K 20% people in the United States have alpha-gal syndrome ¹ See references below 50% of AGS patients reported anaphylactic reactions to alpha-gal containing health products ² 92% of AGS patients had to modify their medications due to their diagnosis ² of AGS patients discuss medication challenges on social media (similar to frequency of food related discussions) ³ For Healthcare Providers If you’re a healthcare provider looking to better support patients with alpha-gal syndrome, visit our HCP page for tailored guidance and resources. Tick bite Weeks to month Consume mammalian meat, dairy, gelatin, or other mammal-derived products Hours and/or Hives, itching, swelling, and/or anaphylaxis Abdominal pain, diarrhea, nausea, vomiting, and/or anaphylaxis Alpha-gal Reaction Pathway Geographic Spread of Tick Species Associated with Alpha-gal Syndrome Adapted from McGill SK et al., Clin Gastroenterol Hepatol. 2021, and Alpha-gal Information (AGI). Frequently Asked Questions about AGS How do you get alpha-gal syndrome? Alpha-gal syndrome is usually triggered by tick bites, especially from the Lone Star Tick (Amblyomma americanum ) in the U.S. Other ticks—like the Asian Longhorned, Black-legged, and Cayenne—plus certain parasites may also play a role. Multiple or repeated tick bites increase the risk, even if past bites caused no reaction. What can trigger a reaction? Mammalian meats, organs, blood Dairy, gelatin, and foods with mammalian byproducts Medications, medical products, personal care, and household items with mammalian ingredients Carrageenan (red seaweed but contains the alpha-gal epitope) Flounder eggs What are the symptoms of alpha-gal syndrome? Hives, itching, or rash Swelling of lips, face, or throat Stomach pain, nausea, vomiting, diarrhea Dizziness, fainting, or drop in blood pressure Anaphylaxis (a life-threatening allergic reaction) How is alpha-gal syndrome diagnosed and managed? Diagnosis Code: ICD-10-CM Z91.014 — Allergy to mammalian meats Testing : Alpha-gal IgE blood test Quest code 10554 | Labcorp code 650001 Full panels (Quest 10555, Labcorp 650003) are rarely needed Avoid incorrect tests like alpha-galactosidase or α-galactosidase A deficiency (for Fabry disease) Management : Avoid mammalian products, carry an epinephrine auto-injector, and prevent tick bites Cure : No cure. Medications and Alpha-gal 75% of medications contain an animal-derived ingredient ⁴ 39% DailyMed of excipient listings are inconsistent ⁵ 50% Manufacturers of ingredient inquiries go unanswered ⁶ 85% of cases: a suitable alternative identified Pill Clarity 10k+ AGS patients helped through our medical information service Resources for Alpha-gal Patients Alpha-gal Friendly Pharmacies A directory of pharmacies partnered with Pill Clarity to help patients find safe, allergen-free medications. Household Items and Ingredients to Avoid Key mammal-derived ingredients to watch for in everyday products. Alpha-gal Friendly Meal Options Find alpha-gal–friendly meal options with PlantStrong, plus get 15% off with code ALPHAGAL15. Online Resources and Support Groups A list of alpha-gal syndrome websites and Facebook support groups for more information and community. Alpha-gal Syndrome: Talks and Insights References ¹Emerging Tick Bite-Associated Meat Allergy Potentially Affects Thousands: Many healthcare providers not familiar with allergic condition. CDC, Jul 2023. ²Uchi, J., Commins, S.P., Wilson, J., et al. "Understanding Health Related Challenges in Patients with Alpha-Gal Syndrome." Poster presentation at the DIA Global Annual Meeting, June 2023. ³Shek, A., Watkins, R., et al. "Frequency of Medication Related Discussions Within Alpha-Gal Social Media Groups" Poster presentation at the American College of Cardiology Conference, April 2024. ⁴Commins, S. P., Uchi, J., & Shah, S. A. Animal-derived ingredients in medicines: A call to action . DIA Global Forum. (2024, March) ⁵Kinsella L, et al. Inconsistent excipient listings in DailyMed. Springer Nature, 2024. ⁶Son FS, et al. Journal of Contemporary Pharmacy Practice, 2023.

< Back Glecaprevir/pibrentasvir Common Brand Names: Mavyret Drug Class Antiviral combinations Animal-free Options? No. Contact Pill Clarity for more information. Indication Acute or chronic hepatitis C virus Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Eszopiclone Common Brand Names: Lunesta Drug Class Miscellaneous anxiolytics, sedatives and hypnotics Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Insomnia Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Akshar Ayurveda Triphala Powder Category Digestive Health, Herbal and Natural Supplements Animal-free? Yes Additional Allergen Information Certified Animal-Free, Cruelty-free, Gluten-Free, Heavy Metal-free, Non-GMO Description CERTIFIED ANIMAL-FREE • A rejuvenating detox with regular digestive cleansing • Rich in natural antioxidants • Supports balanced acidity levels in the digestive tract • Acts as a natural digestive aid to support regularity Active Ingredients Chebulic Myrobalan fruit (Haritaki, terminalia, chebula) Belleric myrobalan fruit (Bibhitaki, terminalia, belerica) Emblic myrobalan fruit (Amalaki, emblica, officinalis) Inactive Ingredients N/A BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back VeganMed Teams Up with Rael and The Pill Club to Offer Animal-Free Women’s Hygiene Products VeganMed, Inc. Jan 1, 2023 VeganMed, Rael, and The Pill Club have joined forces to provide women with access to certified animal-free hygiene products through a convenient mail-order service. VeganMed proudly announces a new collaboration with Rael, a leader in women’s hygiene products, and The Pill Club, a mail-order pharmacy specializing in birth control. This collaboration will provide access to certified animal-free products and support for women’s health. Rael has committed to certifying its relevant products as animal-free, aligning with VeganMed’s mission to provide transparent animal-free choices for consumers. In addition, Rael will be supplying The Pill Club with samples of their certified animal-free products. The Pill Club, known for its convenient and accessible mail-order service, will offer these samples to its patients, empowering them with the choice of animal-free hygiene products alongside their contraceptives. “We’re excited to partner with Rael and The Pill Club to expand access to animal-free women’s hygiene products,” said Jasmine Uchi, PharmD Medical Information and Innovation Fellow at VeganMed. For more information, visit https://www.veganmed.org/post/vegan-friendly-women-s-health-products-for-every-stage-of-life About VeganMed VeganMed promotes transparency in healthcare by providing access to animal-free products. About Rael Rael is a trusted brand in women’s hygiene, offering a range of products that prioritize quality, comfort, and ethical practices. About The Pill Club The Pill Club provides convenient mail-order contraceptive services with personalized care. Previous Next

< Back Interferon beta-1b Common Brand Names: Betaseron, Extavia Drug Class Interferons Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Akshar Ayurveda Bitter Melon Capsules Category Digestive Health, Immune Support Animal-free? Yes Additional Allergen Information Certified Animal-Free, Cruelty-free, Gluten-Free, Heavy Metal-free, Non-GMO Description CERTIFIED ANIMAL-FREE • Supports healthy blood sugar levels • Promotes balanced glucose metabolism • Boosts immune system function • Aids in healthy digestion • Promotes healthy lipid metabolism • Contains natural compounds with antimicrobial properties Active Ingredients Bitter meon (fruit) Inactive Ingredients Starch, PVP K-30, Aerosil, Magnesium Stearate, Sodium Starch glycolate BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Ephedrine Common Brand Names: N/A Drug Class Decongestants, Vasopressors Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Temporary relief of shortness of breath, chest tightness, and wheezing due to bronchial asthma Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Efferdent Plus Mint Anti-Bacterial Denture Cleanser, 90 Tablets Category Oral Care Animal-free? Yes Additional Allergen Information N/A Description • Actively cleans between dentures with an effervescent minty fresh flavor • Removes tough stains in hard to reach places, even in between dentures • First and only denture cleanser tablet brand accepted by the American Dental Association • Kills 99.9 percent of odor causing bacteria • Reduces plaque build up and removes food particles that can cause gum irritation; 90 tablets Active Ingredients Potassium monopersulfate, sodium bicarbonate, and sodium carbonate peroxide Inactive Ingredients N/A BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Ibrexafungerp Common Brand Names: Brexafemme Drug Class Miscellaneous antifungals Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Treat and reduce the number of repeating vaginal yeast infections in women and in girls who have begun having periods Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.