< Back ACC Cardiology Magazine Highlights Hidden Cardiovascular Risks of Alpha-Gal Syndrome Pill Clarity Jul 1, 2025 New article by Pill Clarity Co-founder and CEO Dr. Sachin A. Shah reveals how a tick-borne allergy may accelerate heart disease and complicate cardiac treatment A newly published article in ACC Cardiology Magazine by Dr. Sachin A. Shah, PharmD, FACC , Co-founder and CEO of Pill Clarity, is bringing national attention to the hidden cardiovascular dangers of Alpha-Gal Syndrome (AGS) — a tick-borne allergic condition increasingly recognized as a potential cardiovascular risk factor. AGS, traditionally known for causing delayed allergic reactions to red meat, is now linked to accelerated atherosclerosis, increased plaque vulnerability, and dangerous hypersensitivity to commonly used cardiac medications and devices . “This isn’t just a food allergy,” said Dr. Shah. “Alpha-Gal Syndrome has real, potentially life-threatening implications in cardiology. Yet many clinicians remain unaware.” According to the CDC, an estimated 450,000 Americans may be affected by AGS , with prevalence as high as 35% in certain regions of the southern, midwestern, and mid-Atlantic U.S. Despite this, awareness in cardiology remains limited — and many products used in routine cardiovascular care may pose significant risks to sensitized patients. Highlights from the ACC Cardiology Article: Alpha-gal IgE sensitization was associated with greater atheroma burden and high-risk plaque morphology in two large imaging-based studies. Heparin, gelatin-based surgical products, and animal-derived bioprosthetic valves can cause severe allergic reactions in AGS patients. A 2023 patient survey revealed that 92% of AGS patients had to change medications due to reactions, with 50% reporting anaphylaxis . Excipient-level ingredient transparency is crucial, as some medications contain hidden risks — even seemingly benign drugs like statins or anticoagulants. The Role of Pill Clarity in Supporting Clinicians and Patients Pill Clarity, a free national medical information center , was created to address the growing need for ingredient transparency in medications. Founded by pharmacists, the platform helps patients and healthcare professionals identify mammalian-free and allergy-friendly alternatives to commonly used drugs and over-the-counter products. “At Pill Clarity, we’re solving a problem the healthcare system has overlooked — helping patients find medications that are safe for their unique dietary, religious, or allergic needs,” Dr. Shah explained. Over 75% of AGS-related medication inquiries submitted to Pill Clarity are matched with safe alternatives. The platform also supports 33 million Americans with food allergies , as well as individuals who require vegan, Halal, or Kosher medications. In a landscape where formulations vary between manufacturers, Pill Clarity acts as a trusted partner in helping clinicians make safer, informed decisions. Looking Ahead: Advocacy and Innovation The article underscores the need for updated policies, greater transparency, and proactive care models. Highlights include: A 2023 Citizen Petition to the FDA , calling for mandatory labeling of animal-derived components. Growing interest in bioengineered alpha-gal–free devices for safer valve replacements and vascular grafts. The importance of collaborating with pharmacists and allergists in the perioperative setting, especially in regions with high AGS prevalence. “Until federal regulations catch up, clinicians must lead the way,” Dr. Shah said. “We must ask more questions, verify ingredients, and support patients navigating this complex condition.” About Dr. Sachin A. Shah Dr. Sachin A. Shah, PharmD, FACC is a professor of pharmacy at the University of the Pacific, a cardiovascular researcher, and the Co-founder and CEO of Pill Clarity . With over 100 scientific publications and a passion for health equity, he is leading efforts to bring transparency and patient-centered safety into modern medicine. Read the full article in ACC Cardiology Magazine : “Life-Altering Consequences of a Tick Bite: The Overlooked Cardiac Implications of Alpha-Gal Syndrome” by Dr. Sachin A. Shah, PharmD, FACC – July 2025 Issue Previous Next

< Back Palmer's Cocoa Butter Formula Skin Therapy Oil for Face Category Skincare Animal-free? Yes Additional Allergen Information Paraben-free, phthalate-free, cruelty-free, dye-free Description • Moisturizing Face Oil: Skin Therapy Oil for Face delivers skin restorative oils for multi-purpose, anti-aging skin benefits with ten Pure Oils to help moisturize and smooth fine lines and wrinkles • Special Formula: Made with Cocoa Butter to moisturize, Retinol to reduce the appearance of fine lines and wrinkles, Vitamin C to brighten skin and dark spots, and Cetesomate Complex for essential vitamins and nutrients • Finest Ingredients: We use only the finest natural, raw ingredients for soft, hydrated and beautiful hair & skin. We support sustainable production of Shea & Cocoa Butter and Coconut Oil. You can feel good about what you put on your hair and skin • Choose What's Real: Our nourishing skin care and hair care products feature real, high-quality, plant-based ingredients. Our product line for whole body care includes body butter, creams, balms, lotions, oils, soaps, pregnancy and stretch mark care • Why Palmers? For over 180 years, Palmer's has crafted treatment-oriented beauty products using Cocoa Butter, Coconut Oil, Shea Butter, Olive Oil & Vitamin E to soothe, hydrate, soften, replenish and revitalize skin and hair Active Ingredients Sweet almond oil, Grape seed oil, Isopropyl myristate, Cetearyl ethylhexanoate, Camelina seed oil, Macadamia seed oil, Sesame seed oil, PEG-40 sorbitan peroleate, Coconut oil, Apricot kernel oil, Caprylyl methicone, Cocoa seed butter, Tocopheryl acetate, Retinol, Ascorbyl palmitate, Centella asiatica extract, Rosehip seed extract, Argan oil, Sunflower seed oil, Dimethicone, Hydrogenated methyl abietate, Fragrance, Caprylic/capric triglyceride, BHT, Benzyl benzoate, Citronellol, Alpha-isomethyl ionone, Geraniol, Hydroxyisohexyl 3-cyclohexene carboxaldehyde, Hexyl cinnamal, Butylphenyl methylpropional Inactive Ingredients N/A BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Wellements Organic Nighttime Gripe Water Category Digestive Health, Baby and Kids Care Animal-free? Yes Additional Allergen Information Gluten-Free, Paraben-Free, Artificial Color-Free, Artificial Flavor-Free Description • Herbal Remedy Peaceful Sleep: Almost as good as a lullaby... our herbal remedy uses certified-organic ingredients to safely ease occasional stomach discomfort and gas, those not-so-fun feelings often associated with colic, fussiness, and hiccups. Organic chamomile helps promote peaceful sleep, even for mom and dad. Well tip: Serve before bedtime, then sing "Rock-A-Bye Baby" until your little one starts snoozing. • Recommended for Babies 1+ Month: Works to ease your baby’s tummy troubles so both of you can get some much needed sleep. • Shake well before each use. Use at bedtime. Organic Nighttime Gripe Water may be taken directly using the dispenser provided up to 3 times in a 24-hour period. Wash and dry dispenser thoroughly after each use. We are proud to say our product requires refrigeration after opening as it is free from preservatives — just the way nature designed and the way it should be for your little one! Discard 4 weeks after opening. Suggested Use: Babies 1-6 months: 5 ml, Children 6 months and older: 10 ml • Wellements- Helping families grow and stay healthy, means supporting them with the best products we can produce. To us this means everything we make will be USDA certified organic, made without the use of chemical preservatives and bottled in glass. In doing this, we know we are providing products that truly make a difference. Active Ingredients Sodium, Organic Ginger Root Extract, Organic Fennel Seed Extract, Organic Chamomile Flower Extract (Matricaria chamomilla), Organic Lemon Balm Leaf Extract, and Organic Passionflower Flower Extract. Inactive Ingredients Water, Organic Agave Syrup, Organic Lemon Juice Concentrate, Organic Glycerin, Organic Lemon Juice Powder, and Sodium Bicarbonate. BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Amazon Elements Vegan Biotin 5000 mcg Category Hair Care, Skincare Animal-free? Yes Additional Allergen Information Artificial color/flavor-free, chemical preservative-free, gluten-free Description • ONE BOTTLE CONTAINS: 130 capsules, a 4 month supply (taken daily at the listed serving size). • FOR HAIR, SKIN & NAILS: Helps maintain normal hair, skin, and nails. • SUPPORTS COGNITION: Helps support brain function, cognition, and energy metabolism. Active Ingredients Biotin – 5,000 mcg Inactive Ingredients Microcrystalline Cellulose, Vegetable Capsule (Hydroxypropyl Methylcellulose), Silicon Dioxide BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Pure Mountain Botanicals Cat's Claw 1000 mg High Potency Capsules Category Herbal and Natural Supplements Animal-free? Yes Additional Allergen Information Non-GMO, Magnesium Stearate-Free, Gluten-Free, Sugar-Free, Preservative-Free, Filler-Free Description • MADE with POTENT CAT’S CLAW HERB – Our Kosher certified capsules are filled with Cat Claw Bark Powder (Una de Gato) from remote regions of the Amazon and flaxseed with NOTHING ELSE added. • CONTAINS: Cat’s Claw Capsules - 90 Vegan Kosher Capsules with 500mg per Capsule full-spectrum raw cats claw herb. Active Ingredients Cat's Claw Bark Inactive Ingredients Vegan Capsule, Omega 3 (Flaxseed) BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Garden of Life Raw Iron Category Vitamins and Multivitamins Animal-free? Yes Additional Allergen Information Gluten-free, non-GMO, vegan, Soy-Free Description • Vitamin Code RAW Iron is Non-GMO Project Verified, Certified Vegan, Gluten Free whole food nutrition, specifically formulated with 22mg of gentle, whole food iron—and no high heat, synthetic binders or fillers, artificial flavors, sweeteners, colors or additives commonly used in tablets. RAW Iron is also blended in a base of 23 fruits and vegetables together with food cofactors plus live probiotics and enzymes. • Made with individually 'grown' nutrients utilizing probiotic cultivation to produce RAW Food-Created Nutrients, Vitamin Code supplements are delivered in a whole food base of fruits and vegetables. Vitamin Code supplements are RAW, which not only means that they are produced below 115º F, but also means that these nutrients come with their natural cofactors, along with live probiotics and enzymes, just like raw foods! Vitamin Code raw powders are delivered in capsules without any binders or fillers—everything you want and nothing you don’t want. • Vitamin Code RAW Iron Benefits: • Contains 22mg of gentle whole food iron and whole food vitamins C, B-12 and folate to support iron absorption and utilization†. • Supports blood, heart, eye, immune system and reproductive health†. • Is easy to digest and is stomach-friendly†. • Contains live probiotics and enzymes to support easy, healthy digestion†. Active Ingredients Vitamin C, Folate, Vitamin B12 (Methylcobalamin), Iron (Brown Rice Chelate), and Raw Organic Fruit & Vegetable Blend (Apple, Beet, Broccoli, Carrot, Spinach, Tomato, Strawberry, Tart Cherry, Blackberry, Green Bell Pepper, Brussels Sprout, Blueberry, Ginger, Garlic, Green Onion, Raspberry, Parsley, Cauliflower, Red Cabbage, Kale, Cucumber, Celery, Asparagus), and Raw Probiotic & Enzyme Blend (Lipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, Lactobacillus plantarum, Lactobacillus bulgaricus). Inactive Ingredients Vegetable Cellulose, Organic Rice Hull. BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Isshah Charcoal Bamboo Toothbrush Category Oral Care Animal-free? Yes Additional Allergen Information N/A Description • GO GREEN! – Why fill up landfills with plastic when you don’t have to? Help the environment, and feel better about your mark on this world with Bamboo Toothbrush! It’s the ecological way to not only keep your mouth fresh for just as long as a normal toothbrush, but help the environment at the same time! • PACK OF 12 TOOTHBRUSHES – will last your family a year. Buy a pack of 12 toothbrushes for each person in your household. • SMOOTH & NATURAL BAMBOO HANDLE – will never splinter and is water resistant. Stronger and harder than wood, Bamboo is also more durable and healthier than any plastic. No need to dry the handle after use, just rinse your toothbrush and put back into its holder, just like you would with any other old plastic toothbrush Active Ingredients Charcoal nylon bristles Inactive Ingredients N/A BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Mirikizumab Common Brand Names: Omvoh Drug Class Interleukin inhibitors Animal-free Options? Contact Pill Clarity for more information. Indication Moderately to severely active ulcerative colitis in adults Moderately to severely active Crohn's disease in adults Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Vigabatrin Common Brand Names: Sabril, Vigafyde, Vigpoder, Vigadrone Drug Class Anti-epileptic Animal-free Options? Yes. Contact Pill Clarity for more information. Indication Refractory Complex Partial Seizures (CPS) Infantile Spasms (IS) Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Hydroxyzine Common Brand Names: Atarax, Vistaril Drug Class Antihistamines Animal-free Options? Yes. Contact Pill Clarity for more information. Indication For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states where anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus. As a sedative when used as a premedication and following general anesthesia Contact a Pharmacist Why you need to contact us: Formulations are subject to change, so it's important to consult your healthcare provider or the manufacturer. Our Pill Clarity pharmacists are here to assist. Please note that our product information is general and not a substitute for professional medical advice. Pill Clarity does not assess safety or efficacy of medications. *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back kin+kind Flea and Tick Spray for Dog and Cat, Lemongrass Category Pet Care Animal-free? Yes Additional Allergen Information Sulfate-free Description • PROTECT AND REPEL: Use the power of plants to repel and protect against pests. • PLANT POWERED: This vet-formulated product uses plant-based ingredients for happier pets and a healthier planet. Each ingredient, including every essential oil approved by veternarian to ensure safe concentrations for your pet. • LEMONGRASS AND PEPPERMINT: Natural herbacious and minty fragrance from essential oils. Active Ingredients Lemongrass* Oil 1.50%, Rosemary Oil 0.75%, Cedarwood Oil 0.25 % (*Organic) Inactive Ingredients Water, Polyglyceryl Oleate, Glycerin, Potassium Sorbate, Sodium Benzoate, Xantham Gum, Citric Acid BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.

< Back Sukin Eye Serum Category Eye Care Animal-free? Yes Additional Allergen Information N/A Description Our Antioxidant Eye Serum offers hydration to the delicate eye area through a blend of Plant Extracts including soothing Aloe Vera, Cucumber and Burdock. Nutrient rich Oils of Rosehip, Evening Primrose and Borage assist with reducing the appearance of fine lines and help fight the signs of ageing, while improving the skins texture. Active Ingredients Water (Aqua), Aloe Barbadensis Leaf Juice, Sesamum Indicum (Sesame) Seed Oil, Cetearyl Alcohol, Glycerin, Ceteareth-20, Cetyl Alcohol, Rosa Canina Fruit Oil (Rosehip), Oenothera Biennis (Evening Primrose) Oil, Borago Officinalis Seed Oil (Borage), Tocopherol (Vitamin E), Cucumis Sativus (Cucumber) Fruit Extract, Arctium Lappa Root Extract (Burdock), Urtica Dioica (Nettle) Leaf Extract, Xanthan Gum, Citric Acid, Phenoxyethanol, and Benzyl Alcohol Inactive Ingredients N/A BUY NOW *The product and/or information provided on Pill Clarity is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Pill Clarity does not assess safety or efficacy of medications. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product.